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1

Pilocarpine prodrugs II. Synthesis, stability, bioconversion, and physicochemical properties of sequentially labile pilocarpine acid diesters

Hans Bundgaard, Erik Falch, Claus Larsen, Gerold L. Mosher, Thomas J. Mikkelson

Journal:

Journal of Pharmaceutical Sciences

Year:

1986

Language:

english

File:

PDF, 975 KB

english, 1986

2

Prodrugs as drug delivery systems XXV: Hydrolysis of oxazolidines—a potential new prodrug type

Marianne Johansen, Hans Bundgaard

Journal:

Journal of Pharmaceutical Sciences

Year:

1983

Language:

english

File:

PDF, 558 KB

english, 1983

3

Kinetics and Pattern of Degradation of Thyrotropin-Releasing Hormone (TRH) in Human Plasma

Judi Møss, Hans Bundgaard

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 828 KB

1990

4

Prodrugs of Peptides. 18. Synthesis and Evaluation of Various Esters of Desmopressin (dDAVP)

Anne H. Kahns, Anders Buur, Hans Bundgaard

Journal:

Pharmaceutical Research

Year:

1993

File:

PDF, 1.22 MB

1993

5

Kinetics and mechanism of the acid-base equilibrium of mexazolam analogues: A modification of the mechanism proposed previously for mexazolam

Yukihisa Kurono, Hiroshi Tamaki, Tomonari Kuwayama, Tomoko Ichii, Hiroshi Sawabe, Tamotsu Yashiro, Ken Ikeda, Hans Bundgaard

Journal:

International Journal of Pharmaceutics

Year:

1992

Language:

english

File:

PDF, 551 KB

english, 1992

6

Cyclization-activated phenyl carbamate prodrug forms for protecting phenols against first-pass metabolism

Karin Fredholt Thomsen, Hans Bundgaard

Journal:

International Journal of Pharmaceutics

Year:

1993

Language:

english

File:

PDF, 760 KB

english, 1993

7

Evaluation of glycolamide esters and various other esters of aspirin as true aspirin prodrugs

Moerk Nielsen, Niels, Bundgaard, Hans

Journal:

Journal of Medicinal Chemistry

Year:

1989

Language:

english

File:

PDF, 887 KB

english, 1989

8

Kinetics of the acid-catalyzed hydrolysis of doxorubicin

Wassermann, Karsten, Bundgaard, Hans

Journal:

International Journal of Pharmaceutics

Year:

1983

Language:

english

File:

PDF, 450 KB

english, 1983

9

Pro-drugs as drug delivery systems XI. Preparation and characterization of a novel water-soluble pro-drug type for barbituric acids

Bundgaard, Hans, Falch, Erik, Larsen, Claus

Journal:

International Journal of Pharmaceutics

Year:

1980

Language:

english

File:

PDF, 671 KB

english, 1980

10

Acetylsalicylsalicylic acid: a potentially immunogenic impurity in acetylsalicylic acid

BUNDGAARD, HANS

Journal:

Journal of Pharmacy and Pharmacology

Year:

1974

Language:

english

File:

PDF, 339 KB

english, 1974

11

Kinetic demonstration of a metastable intermediate in isomerization of penicillin to penicillenic acid in aqueous solution

Journal:

Journal of Pharmaceutical Sciences

Year:

1971

Language:

english

File:

PDF, 299 KB

english, 1971

12

Intramolecular and intermolecular transformations of aspirin in nonhydroxylic solvents

Hans Bundgaard, Claus Larsen

Journal:

Journal of Pharmaceutical Sciences

Year:

1976

Language:

english

File:

PDF, 331 KB

english, 1976

13

Prodrugs as drug delivery systems IV: N-mannich bases as potential novel prodrugs for amides, ureides, amines, and other NH-acidic compounds

Hans Bundgaard, Marianne Johansen

Journal:

Journal of Pharmaceutical Sciences

Year:

1980

Language:

english

File:

PDF, 308 KB

english, 1980

14

Pilocarpine prodrugs I. Synthesis, physicochemical properties and kinetics of lactonization of pilocarpic acid esters

Hans Bundgaard, Erik Falch, Glaus Larsen, Thomas J. Mikkelson

Journal:

Journal of Pharmaceutical Sciences

Year:

1986

Language:

english

File:

PDF, 858 KB

english, 1986

15

Prodrugs of 5-fluorouracil V. 1-Alkoxycarbonyl derivatives as potential prodrug forms for improved rectal or oral delivery of 5-fluorouracil

Anders Buur, Hans Bundgaard

Journal:

Journal of Pharmaceutical Sciences

Year:

1986

Language:

english

File:

PDF, 632 KB

english, 1986

16

Glycolamide esters as biolabile prodrugs of carboxylic acid agents: Synthesis, stability, bioconversion, and physicochemical properties

Niels Mørk Nielsenw, Hans Bundgaard

Journal:

Journal of Pharmaceutical Sciences

Year:

1988

Language:

english

File:

PDF, 1.35 MB

english, 1988

17

Prodrugs of peptides IV: Bioreversible derivatization of the pyroglutamyl group by N-acylation and N-aminomethylation to effect protection against pyroglutamyl aminopeptidase

Hans Bundgaard, Judi Møss

Journal:

Journal of Pharmaceutical Sciences

Year:

1989

Language:

english

File:

PDF, 589 KB

english, 1989

18

Carbamate ester prodrugs of dopaminergic compounds: Synthesis, stability, and bioconversion

Kristian T. Hansen, Peter Faarup, Hans Bundgaard

Journal:

Journal of Pharmaceutical Sciences

Year:

1991

Language:

english

File:

PDF, 653 KB

english, 1991

19

Decidable Fragments of a Higher Order Calculus with Locations

Mikkel Bundgaard, Jens Chr. Godskesen, Bjørn Haagensen, Hans Hüttel

Journal:

Electronic Notes in Theoretical Computer Science

Year:

2009

Language:

english

File:

PDF, 478 KB

english, 2009

20

A new spectrophotometric method for the selective determination of ampicillin, amoxycillin and cyclacillin in the presence of polymers and other degradation products

Hans Bundgaard, Claus Larsen

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

1983

Language:

english

File:

PDF, 557 KB

english, 1983

21

Rate and mode of basic hydrolysis of anhydropenicillin

Hans Bundgaard, Helle R. Angelo

Journal:

Tetrahedron Letters

Year:

1974

Language:

english

File:

PDF, 203 KB

english, 1974

22

Imidazole-catalyzed isomerization of penicillins into penicillenic acids

Journal:

Tetrahedron Letters

Year:

1971

Language:

english

File:

PDF, 203 KB

english, 1971

23

Protection of the peptide bond against α-chymotrypsin by the prodrug approach

Anne H. Kahns, Gitte J. Friis, Hans Bundgaard

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 257 KB

english, 1993

24

Differences in investigations of sudden unexpected deaths in young people in a nationwide setting

Bo Gregers Winkel, Anders Gaarsdal Holst, Juliane Theilade, Ingrid Bayer Kristensen, Jørgen Lange Thomsen, Hans Petter Hougen, Henning Bundgaard, Jesper Hastrup Svendsen, Stig Haunsø, Jacob Tfelt-Hans

Journal:

International Journal of Legal Medicine

Year:

2012

Language:

english

File:

PDF, 233 KB

english, 2012

25

An inter-laboratory stability study of roll-to-roll coated flexible polymer solar modules

Suren A. Gevorgyan, Andrew J. Medford, Eva Bundgaard, Subarna B. Sapkota, Hans-Frieder Schleiermacher, Birger Zimmermann, Uli Würfel, Amine Chafiq, Monica Lira-Cantu, Thomas Swonke, Michael Wagner, Ch

Journal:

Solar Energy Materials and Solar Cells

Year:

2011

Language:

english

File:

PDF, 3.29 MB

english, 2011

26

Polymerization of penicillins : V. Separation, identification and quantitative determination of antigenic polymerization products in ampicillin sodium preparations by high-performance liquid chromatography

Claus Larsen, Hans Bundgaard

Journal:

Journal of Chromatography A

Year:

1978

Language:

english

File:

PDF, 557 KB

english, 1978

27

Polymerization of penicillins : IV. Separation, isolation and characterization of ampicillin polymers formed in aqueous solution

Hans Bundgaard, Claus Larsen

Journal:

Journal of Chromatography A

Year:

1977

Language:

english

File:

PDF, 631 KB

english, 1977

28

Formaldehyde in a hypoallergenic non-woven textile acrylate tape

Klaus E. Andersen, Niels Hjorth, Hans Bundgaard, Marianne Johansen

Journal:

Contact Dermatitis

Year:

1983

File:

PDF, 119 KB

1983

29

Allergic contact dermatitis from formaldehyde in Fucidin® ointment

Klaus E. Andersen, Hans Bundgaard, Marianne Johansen

Journal:

Contact Dermatitis

Year:

1983

File:

PDF, 220 KB

1983

30

Prodrugs of Peptides. 9. BioreversibleN-α-Hydroxyalkylation of the Peptide Bond to Effect Protection Against Carboxypeptidase or Other Proteolytic Enzymes

Hans Bundgaard, GitteJuel Rasmussen

Journal:

Pharmaceutical Research

Year:

1991

File:

PDF, 1.43 MB

1991

31

Water-Soluble, Solution-Stable, and BiolabileN-Substituted (Aminomethyl)benzoate Ester Prodrugs of Acyclovir

Hans Bundgaard, Ejvind Jensen, Erik Falch

Journal:

Pharmaceutical Research

Year:

1991

File:

PDF, 1.03 MB

1991

32

Prodrugs of Peptides. 11. Chemical and Enzymatic Hydrolysis Kinetics ofN-Acyloxymethyl Derivatives of a Peptide-like Bond

Hans Bundgaard, Gitte Juel Rasmussen

Journal:

Pharmaceutical Research

Year:

1991

File:

PDF, 695 KB

1991

33

Role of Enzymatic Lability in the Corneal and Conjunctival Penetration of Timolol Ester Prodrugs in the Pigmented Rabbit

Du-Shieng Chien, Hitoshi Sasaki, Hans Bundgaard, Anders Buur, Vincent H. L. Lee

Journal:

Pharmaceutical Research

Year:

1991

File:

PDF, 908 KB

1991

34

Prodrugs of Peptides. 13. Stabilization of Peptide Amides Against α-Chymotrypsin by the Prodrug Approach

Anne H. Kahns, Hans Bundgaard

Journal:

Pharmaceutical Research

Year:

1991

File:

PDF, 1.02 MB

1991

35

Stereoselective Enzymatic Hydrolysis of Various Ester Prodrugs of Ibuprofen and Flurbiprofen in Human Plasma

Niels Mørk, Hans Bundgaard

Journal:

Pharmaceutical Research

Year:

1992

File:

PDF, 789 KB

1992

36

Prodrugs of Peptides. 6. Bioreversible Derivatives of Thyrotropin-Releasing Hormone (TRH) with Increased Lipophilicity and Resistance to Cleavage by the TRH-Specific Serum Enzyme

Hans Bundgaard, Judi Møss

Journal:

Pharmaceutical Research

Year:

1990

File:

PDF, 1.22 MB

1990

37

Drug Delivery Studies in Caco-2 Monolayers. Synthesis, Hydrolysis, and Transport of O-Cyclopropane Carboxylic Acid Ester Prodrugs of Various β-Blocking Agents

Lars Hovgaard, Helle Brøndsted, Anders Buur, Hans Bundgaard

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.04 MB

1995

38

The double prodrug concept and its applications

Journal:

Advanced Drug Delivery Reviews

Year:

1989

Language:

english

File:

PDF, 1.26 MB

english, 1989

39

(C) Means to enhance penetration: (1) Prodrugs as a means to improve the delivery of peptide drugs

Journal:

Advanced Drug Delivery Reviews

Year:

1992

Language:

english

File:

PDF, 1.82 MB

english, 1992

40

Allopurinol prodrugs. V. Water-soluble N-substituted (aminomethyl)benzoyloxymethyl allopurinol derivatives for parenteral or rectal delivery

Hans Bundgaard, Ejvind Jensen, Erik Falch, Søren B. Pedersen

Journal:

International Journal of Pharmaceutics

Year:

1990

Language:

english

File:

PDF, 1.20 MB

english, 1990

41

Prodrugs of peptides. 7. Transdermal delivery of thyrotropin-releasing hormone (TRH) via prodrugs

Judi Møss, Hans Bundgaard

Journal:

International Journal of Pharmaceutics

Year:

1990

Language:

english

File:

PDF, 477 KB

english, 1990

42

Prodrugs of peptides. 8. In vitro study of intestinal metabolism and penetration of thyrotropin-releasing hormone (TRH) and its prodrugs

Judi Møss, Anders Buur, Hans Bundgaard

Journal:

International Journal of Pharmaceutics

Year:

1990

Language:

english

File:

PDF, 620 KB

english, 1990

43

Peptide esters as water-soluble prodrugs for hydroxyl containing agents: Chemical stability and enzymatic hydrolysis of benzyl esters of glycine, diglycine and triglycine

Ejvind Jensen, Hans Bundgaard

Journal:

International Journal of Pharmaceutics

Year:

1991

Language:

english

File:

PDF, 671 KB

english, 1991

44

Utilization of prodrugs to enhance the transdermal absorption of morphine

Jørn Drustrup, Ann Fullerton, Lona Christrup, Hans Bundgaard

Journal:

International Journal of Pharmaceutics

Year:

1991

Language:

english

File:

PDF, 985 KB

english, 1991

45

N-Acyl derivatives as prodrug forms for amides: Chemical stability and enzymatic hydrolysis of various N-acyl and N-alkoxycarbonyl amide derivatives

Anne H. Kahns, Hans Bundgaard

Journal:

International Journal of Pharmaceutics

Year:

1991

Language:

english

File:

PDF, 922 KB

english, 1991

46

Prodrugs of peptides. 10. Protection of di- and tripeptides against aminopeptidase by formation of bioreversible 4-imidazolidinone derivatives

Gitte Juel Rasmussen, Hans Bundgaard

Journal:

International Journal of Pharmaceutics

Year:

1991

Language:

english

File:

PDF, 655 KB

english, 1991

47

Aminomethylbenzoate esters of chloramphenicol as a novel prodrug type for parenteral administration

Ejvind Jensen, Hans Bundgaard

Journal:

International Journal of Pharmaceutics

Year:

1991

Language:

english

File:

PDF, 782 KB

english, 1991

48

Facile α-chymotrypsin-catalyzed degradation of the HIV inhibitor [d-Ala1]-Peptide T amide

Anne H. Kahns, Hans Bundgaard

Journal:

International Journal of Pharmaceutics

Year:

1991

Language:

english

File:

PDF, 471 KB

english, 1991

49

Prodrugs of peptides. 15. 4-Imidazolidinone prodrug derivatives of enkephalins to prevent aminopeptidase-catalyzed metabolism in plasma and absorptive mucosae

Gitte Juel Rasmussen, Hans Bundgaard

Journal:

International Journal of Pharmaceutics

Year:

1991

Language:

english

File:

PDF, 853 KB

english, 1991

50

Oral bioavailability of 17β-estradiol and various ester prodrugs in the rat

Kenneth B. Lokind, Finn Hjort Lorenzen, Hans Bundgaard

Journal:

International Journal of Pharmaceutics

Year:

1991

Language:

english

File:

PDF, 394 KB

english, 1991